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Neurobiology of Obesity

Obesity is a worldwide epidemic. It is multifactorial and yields significant medical consequences, including diabetes, cardiovascular disease, liver disease, and even cancer. Few therapies have emerged to treat obesity, but this is not surprising because we cannot fix a problem that we do not fully understand.

The brain is a vital organ that controls how much we eat and how many calories we burn. However, eating is a very complex behaviour. We eat when we are hungry, but do not eat only when we are hungry, and there lies the problem. In the Chee lab, we tackle this problem by studying the homeostatic factors that control hunger; the hedonic factors that stimulate or curb appetite; as well as how food nutrition delivers brain signals to promote healthy or unhealthy behaviors.

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